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Gamers crack AIDS enzyme

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Acquired Immune Deficiency Syndrome.

It should be called STIDS (Sexually Transmitted Immune Deficiency Syndrome). It's slightly unspecific for laymans. Though they got their bases covered with STI's and STD's. At a loss, my friends.

AIDS is a disease, manufactured. No? I have no idea. However it is spread I have absolutely no fathoming of the concept. I have not been infected, nor do I want to be. It seems, however, that the deception of the media and the internet has blown this whole thing out of proportion. Also, the idea that gamers have deciphered this enzyme or what not, I am not able to wrap my head around that. Is this meant to be a joke? No.

Seriously folks, what kind of downward spiral are we in here? If this is positive progression and scientific advancement, my whole-hearted apologies for my trivial assumption of all this, but I've heard so much utter garbage over the internet that it's hard not to be cynical. I really have to dig deep here.

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AIDS isn't just sexually transmitted. You can get it from blood transfusions, and mothers can pass it onto their children during pregnancy.

Granted, it's most widespread cause is sexual deviants it's not always the case.

Also, the idea that gamers have deciphered this enzyme or what not, I am not able to wrap my head around that. Is this meant to be a joke? No.

No.

Figuring out the structure of proteins is vital for understanding the causes of many diseases and developing drugs to block them.

But a microscope gives only a flat image of what to the outsider looks like a plate of one-dimensional scrunched-up spaghetti. Pharmacologists, though, need a 3-D picture that "unfolds" the molecule and rotates it in order to reveal potential targets for drugs.

This is where Foldit comes in (and gamers).

Gamers using the Foldit game, were able to 3D map that flat one dimensional image that was necessary in cracking the AIDS enzyme. It goes a bit beyond that, too. It needed to be a 'roadmap' that not only worked, but had a low energy amino acid structure for the proteins in that enzyme. The amount of possible builds is astronomical in number.

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